OKBET SPORTS ODDS | Week 2 Chargers vs. Chiefs Betting Prediction: A High-Scoring AFC West Showdown

Week 2 Chargers vs. Chiefs Betting Prediction: A High-Scoring AFC West Showdown


Week 1 of the 2022 NFL season had numerous unforgettable moments for football lovers. Those are, however, in the rearview mirror as Week 2 begins in a few days. A Thursday Night Football matchup between two AFC West rivals, the Kansas City Chiefs and the Los Angeles Chargers, is one to look forward to.


The Chargers won their first game of the season, defeating the Las Vegas Raiders 24-19. In the win, Justin Herbert completed 26 passes for 279 yards and three touchdowns, while Khalil Mack recorded three sacks in his Los Angeles debut.

The Chiefs also had a successful start to the season, defeating the Arizona Cardinals 44-21. Patrick Mahomes demonstrated that he does not require Tyreek Hill to be effective, completing five touchdown passes to four different teammates.

Fortunately, Betting News has compiled the most recent Chargers vs. Chiefs odds from FanDuel Sportsbook, as well as a forecast and top bets for the NFL Week 2 matchup.

Week 2 Matchup Information and Betting Odds for the Los Angeles Chargers vs. Kansas City Chiefs
Matchup Specifics

Los Angeles Chargers (1-0, 0-0 at home) vs. Kansas City Chiefs (1-0, 0-0 Home)
GEHA Field at Arrowhead Stadium is the venue and location (Kansas City, Missouri)
Thursday, September 15, 2022
8:15 p.m. game time Eastern Standard Time
Chargers vs. Chiefs Game Information: Prime Video, NFL+

Odds for Chargers vs. Chiefs
The game odds are provided by Okbet Sports Betting. This article may also include odds from other big okbet online betting.


  • Los Angeles Chargers +3.5 (-110)
  • Kansas City Chiefs -3.5 (-110)


  • Over 54.5 (-105)
  • Under 54.5 (-115)


  • Los Angeles Chargers +160
  • Kansas City Chiefs -190

Chargers vs. Chiefs Betting Trends

  • The Chargers are 3-13 straight up in their last 16 games against Kansas City.
  • Kansas City is 8-1 straight up in its last nine home games.
  • The Chargers are 4-8 against the spread (ATS) in their last 12 games.
  • Kansas City is 2-5 ATS in its last seven games against the Chargers.
  • The total has hit the over in each of the Chargers’ last six games.
  • The total has hit the under in 12 of Kansas City’s last 18 Week 2 matchups.

Predictions and picks for the Los Angeles Chargers vs. Kansas City Chiefs
Prediction for Chargers against. Chiefs: Chiefs 34, Chargers 28

Picks for the Chargers vs. Chiefs: Chiefs -3.5 (Best Value: -110 at FanDuel) & Over 54.5 Points (Best Value: -105 at FanDuel)

Last week, the Chargers and Chiefs appeared to be the top teams in the AFC West. Mahomes and Herbert are on completely different levels, and it would not be surprising if both gunslingers attempted to outdo each other on Thursday night.

Fans were concerned about Mahomes’ ability to be productive without Hill, but he plainly demonstrated that this is not the case. He completed eight throws for 121 yards and a touchdown to Travis Kelce. Mahomes even got along with offseason acquisition JuJu Smith-Schuster, who had 79 yards on six receptions.

Most importantly, running back Clyde Edwards-Helaire shown that he can contribute to the passing game. The third-year runner has three receptions, two for touchdowns.

Even Kansas City’s defense looked better this year than it did last. The Cardinals have offensive promise, but the Chiefs limited them to only seven points and 282 total yards through three quarters.

Last week, the Chargers offense looked strong as well, generating 355 total yards. However, the running game must improve. Starting running back Austin Ekeler only averaged 2.6 yards per carry on 14 attempts, which is surprising given that he had averaged 5.2 yards per carry in eight career games versus Kansas City.

Unfortunately, the Chargers’ offense could be depleted in Week 2. Keenan Allen, the team’s No. 1 wide receiver, had a hamstring injury last week and it’s unknown whether he’ll play due to the short turnaround.

If the offense is depleted, the Chargers’ defense must do everything it can to slow Mahomes down. Players like Mack and Joey Bosa will need to go through the Chiefs’ offensive line early and frequently, while defensive backs Asante Samuel Jr. and Derwin James will need to shut down the opposing pass-catchers.

Thursday Night Football games can be entertaining, so expect Mahomes and Herbert to put on a show. At the end of the day, I believe the Chiefs will win a shootout because they are healthier than their AFC West competitors.

Aside from selecting the Chiefs as 3.5-point favorites, taking the over on the total is a good option. Since Herbert was drafted, the average total in Chargers-Chiefs games has been 57 points.


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